Anti-Histone
Anti-Histone is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against histone proteins in human serum or plasma.
Up to 80 % of patients suffering from systemic lupus erythematosus (SLE) and nearly 95 % of patients with drug-induced lupus (DIL) have autoantibodies against histone proteins in their antibody profile.
Histone antibodies are not specific to a particular disease. Aside from SLE and DIL, they also occur in patients with numerous other rheumatic diseases, including rheumatoid arthritis, juvenile chronic arthritis, and scleroderma.
	
			
		Specifications
		
		
		
			
			
				| Product Number | 
						ORG 207 | 
			 
												
				
					| Tests | 24 Alegria® strips | 
				 
																			
				
					| Calibration | WHO MRC 66/233 | 
				 
																			
				
					| Calculation | quantitative | 
				 
																			
				
					| Range | 0 - 200 U/ml | 
				 
																			
				
					| Cut-off | 40 U/ml | 
				 
															
							| Coating | 
							
					histone proteins H1, H2A, H2B, H3, H4				 | 				
			 
				 
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					Instruction for Use Revision 4. Earlier versions and additional languages can be found in the document archive.
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