Anti-Phosphatidyl Inositol IgG/IgM
Anti-Phosphatidyl Inositol IgG/IgM is an ELISA test for the quantitative determination of IgG and IgM antibodies against phosphatidyl inositol in human serum or plasma.
Autoantibodies against phosphatidyl inositol, a negatively charged phospholipid, generally appear together with cardiolipin antibodies and antibodies against phosphatidyl serine. However, anti-phosphatidyl inositol has also been detected by itself in patients with antiphospholipid syndrome (APS).
In the absence of anti-cardiolipin and anti-phosphatidyl serine, the detection of phosphatidyl inositol is thus indicative of APS.
In addition to the antigen, the wells of the ORGENTEC Anti-Phosphatidyl Inositol test are also coated with human beta-2-glycoprotein I as cofactor.
Specifications
| Product Number |
ORG 536 |
| Tests | 12 x 8 tests |
| Calibration | Harris sera, IRP 97/656 (IgG), HCAL (IgG) / EY2C9 (IgM) |
| Calculation | quantitative |
| Range | IgG: 0 - 100 GPL-U/ml; IgM: 0 - 100 MPL-U/ml |
| Cut-off | 10 GPL-U/ml; IgM: 7 MPL-U/ml |
| Coating |
phosphatidyl inositol |
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Instruction for Use Revision 3. Earlier versions and additional languages can be found in the document archive.
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