Anti-SS-B

Anti-SS-B is an ELISA test for the quantitative determination of IgG antibodies against SS-B in human serum or plasma.

SS-B antigens are extractable nuclear antigens (ENA), and antibodies against SS-B are used for the differential diagnosis and monitoring of systemic inflammatory autoimmune diseases. Autoantibodies against the SS-B protein are found in cases of Sjoegren’s syndrome and various forms of lupus erythematosus. The diagnostic sensitivity of the marker for primary Sjoegren’s syndrome is 70 % and 50 % for secondary Sjoegren’s syndrome. SS-B antibodies are usually found together with anti-SS-A. In asymptomatic individuals who are suspected to have Sjoegren’s syndrome, SS-B antibodies can precede the full picture of the disease.

Specifications